Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia

Intrahepatic cholestasis of pregnancy (ICP) is characterized by elevated maternal circulating bile acid levels and associated dyslipidemia. ICP leads to accumulation of bile acids in the fetal compartment, and the elevated bile acid concentrations are associated with an increased risk of adverse fet...

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Dades bibliogràfiques
Publicat a:Am J Physiol Gastrointest Liver Physiol
Autors principals: Pataia, Vanessa, McIlvride, Saraid, Papacleovoulou, Georgia, Ovadia, Caroline, McDonald, Julie A. K., Wahlström, Annika, Jansen, Eugène, Adorini, Luciano, Shapiro, David, Marchesi, Julian R., Marschall, Hanns-Ulrich, Williamson, Catherine
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500267/
https://ncbi.nlm.nih.gov/pubmed/32597707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00126.2020
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