Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia

Intrahepatic cholestasis of pregnancy (ICP) is characterized by elevated maternal circulating bile acid levels and associated dyslipidemia. ICP leads to accumulation of bile acids in the fetal compartment, and the elevated bile acid concentrations are associated with an increased risk of adverse fet...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Pataia, Vanessa, McIlvride, Saraid, Papacleovoulou, Georgia, Ovadia, Caroline, McDonald, Julie A. K., Wahlström, Annika, Jansen, Eugène, Adorini, Luciano, Shapiro, David, Marchesi, Julian R., Marschall, Hanns-Ulrich, Williamson, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500267/
https://ncbi.nlm.nih.gov/pubmed/32597707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00126.2020
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