Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy

Ursodeoxycholic acid (UDCA) treatment can reduce itch and lower endogenous serum bile acids in intrahepatic cholestasis of pregnancy (ICP). We sought to determine how it could influence the gut environment in ICP to alter enterohepatic signalling. The gut microbiota and bile acid content were determ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ovadia, Caroline, Perdones-Montero, Alvaro, Fan, Hei Man, Mullish, Benjamin H., McDonald, Julie A. K., Papacleovoulou, Georgia, Wahlström, Annika, Ståhlman, Marcus, Tsakmaki, Anastasia, Clarke, Louise C. D., Sklavounos, Alexandros, Dixon, Peter H., Bewick, Gavin A., Walters, Julian R. F., Marschall, Hanns-Ulrich, Marchesi, Julian R., Williamson, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054423/
https://ncbi.nlm.nih.gov/pubmed/32127609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60821-w
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