Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2(−/−) mice by modulating composition, signalling and excretion of faecal bile acids

BACKGROUND AND AIMS: Interruption of the enterohepatic circulation of bile acids (BAs) may protect against BA-mediated cholestatic liver and bile duct injury. BA sequestrants are established to treat cholestatic pruritus, but their impact on the underlying cholestasis is still unclear. We aimed to e...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Gut
Main Authors: Fuchs, Claudia Daniela, Paumgartner, Gustav, Mlitz, Veronika, Kunczer, Victoria, Halilbasic, Emina, Leditznig, Nadja, Wahlström, Annika, Ståhlman, Marcus, Thüringer, Andrea, Kashofer, Karl, Stojakovic, Tatjana, Marschall, Hanns-Ulrich, Trauner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Hepatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109278/
https://ncbi.nlm.nih.gov/pubmed/29636383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-314553
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados