p62/SQSTM1 Differentially Removes the Toxic Mutant Androgen Receptor via Autophagy and Inclusion Formation in a Spinal and Bulbar Muscular Atrophy Mouse Model

Polyglutamine (polyQ) diseases are inherited neurodegenerative disorders that are caused by the expansion of trinucleotide CAG repeats in the causative genes. Spinal and bulbar muscular atrophy (SBMA) is an inherited motor neuron disease that is caused by the expansion of a polyQ tract within the an...

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Foilsithe in:J Neurosci
Main Authors: Doi, Hideki, Adachi, Hiroaki, Katsuno, Masahisa, Minamiyama, Makoto, Matsumoto, Shinjiro, Kondo, Naohide, Miyazaki, Yu, Iida, Madoka, Tohnai, Genki, Qiang, Qiang, Tanaka, Fumiaki, Yanagawa, Toru, Warabi, Eiji, Ishii, Tetsuro, Sobue, Gen
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2013
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618982/
https://ncbi.nlm.nih.gov/pubmed/23637164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3021-12.2013
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