p62/SQSTM1 Differentially Removes the Toxic Mutant Androgen Receptor via Autophagy and Inclusion Formation in a Spinal and Bulbar Muscular Atrophy Mouse Model

Polyglutamine (polyQ) diseases are inherited neurodegenerative disorders that are caused by the expansion of trinucleotide CAG repeats in the causative genes. Spinal and bulbar muscular atrophy (SBMA) is an inherited motor neuron disease that is caused by the expansion of a polyQ tract within the an...

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Publicado no:J Neurosci
Main Authors: Doi, Hideki, Adachi, Hiroaki, Katsuno, Masahisa, Minamiyama, Makoto, Matsumoto, Shinjiro, Kondo, Naohide, Miyazaki, Yu, Iida, Madoka, Tohnai, Genki, Qiang, Qiang, Tanaka, Fumiaki, Yanagawa, Toru, Warabi, Eiji, Ishii, Tetsuro, Sobue, Gen
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618982/
https://ncbi.nlm.nih.gov/pubmed/23637164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3021-12.2013
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