CHIP Overexpression Reduces Mutant Androgen Receptor Protein and Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model

Spinal and bulbar muscular atrophy (SBMA) is an inherited motor neuron disease caused by the expansion of a polyglutamine tract within the androgen receptor (AR). The pathologic features of SBMA are motor neuron loss in the spinal cord and brainstem and diffuse nuclear accumulation and nuclear inclu...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Adachi, Hiroaki, Waza, Masahiro, Tokui, Keisuke, Katsuno, Masahisa, Minamiyama, Makoto, Tanaka, Fumiaki, Doyu, Manabu, Sobue, Gen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2007
Onderwerpen:
Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672370/
https://ncbi.nlm.nih.gov/pubmed/17494697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1242-07.2007
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items