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Huntingtin Mediates Anxiety/Depression-Related Behaviors and Hippocampal Neurogenesis
Huntington disease (HD) is associated with early psychiatric symptoms including anxiety and depression. Here, we demonstrate that wild-type huntingtin, the protein mutated in HD, modulates anxiety/depression-related behaviors according to its phosphorylation at serines 1181 and 1201. Genetic phospho...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Neurosci |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Society for Neuroscience
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6618836/ https://ncbi.nlm.nih.gov/pubmed/23678106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5110-12.2013 |
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