FAIM-L Is an IAP-Binding Protein That Inhibits XIAP Ubiquitinylation and Protects from Fas-Induced Apoptosis

The neuronal long isoform of Fas Apoptotic Inhibitory Molecule (FAIM-L) protects from death receptor (DR)-induced apoptosis, yet its mechanism of protection remains unknown. Here, we show that FAIM-L protects rat neuronal Type II cells from Fas-induced apoptosis. XIAP has previously emerged as a mol...

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Publicat a:J Neurosci
Autors principals: Moubarak, Rana S., Planells-Ferrer, Laura, Urresti, Jorge, Reix, Stéphanie, Segura, Miguel F., Carriba, Paulina, Marqués-Fernàndez, Fernando, Sole, Carme, Llecha-Cano, Nuria, Lopez-Soriano, Joaquin, Sanchis, Daniel, Yuste, Victor J., Comella, Joan X.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618789/
https://ncbi.nlm.nih.gov/pubmed/24305822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2479-13.2013
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