SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L

The long isoform of Fas apoptosis inhibitory molecule (FAIM-L) is a neuron-specific death receptor antagonist that modulates apoptotic cell death and mechanisms of neuronal plasticity. FAIM-L exerts its antiapoptotic action by binding to X-linked inhibitor of apoptosis protein (XIAP), an inhibitor o...

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Udgivet i:Cell Death Dis
Main Authors: Coccia, Elena, Planells-Ferrer, Laura, Badillos-Rodríguez, Raquel, Pascual, Marta, Segura, Miguel F., Fernández-Hernández, Rita, López-Soriano, Joaquin, Garí, Eloi, Soriano, Eduardo, Barneda-Zahonero, Bruna, Moubarak, Rana S., Pérez-García, M. Jose, Comella, Joan X.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997380/
https://ncbi.nlm.nih.gov/pubmed/32015347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2282-x
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