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Localized and Collective Motions in HET‐s(218‐289) Fibrils from Combined NMR Relaxation and MD Simulation

Nuclear magnetic resonance (NMR) relaxation data and molecular dynamics (MD) simulations are combined to characterize the dynamics of the fungal prion HET‐s(218‐289) in its amyloid form. NMR data is analyzed with the dynamics detector method, which yields timescale‐specific information. An analogous...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Smith, Albert A., Ernst, Matthias, Riniker, Sereina, Meier, Beat H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618077/
https://ncbi.nlm.nih.gov/pubmed/31070275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201901929
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