Dynactin1 depletion leads to neuromuscular synapse instability and functional abnormalities

BACKGROUND: Dynactin subunit 1 is the largest subunit of the dynactin complex, an activator of the molecular motor protein complex dynein. Reduced levels of DCTN1 mRNA and protein have been found in sporadic amyotrophic lateral sclerosis (ALS) patients, and mutations have been associated with diseas...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Mol Neurodegener
Autors principals: Bercier, Valérie, Hubbard, Jeffrey M., Fidelin, Kevin, Duroure, Karine, Auer, Thomas O., Revenu, Céline, Wyart, Claire, Del Bene, Filippo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617949/
https://ncbi.nlm.nih.gov/pubmed/31291987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0327-3
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars