FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation

Neuronal connectivity relies on molecular motor-based axonal transport of diverse cargoes. Yet the precise players and regulatory mechanisms orchestrating such trafficking events remain largely unknown. We here report the ATPase Fignl1 as a novel regulator of bidirectional transport during axon navi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: Atkins, Melody, Gasmi, Laïla, Bercier, Valérie, Revenu, Céline, Del Bene, Filippo, Hazan, Jamilé, Fassier, Coralie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781435/
https://ncbi.nlm.nih.gov/pubmed/31541015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201805128
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