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Hyperglycemia‐Triggered Sphingosine‐1‐Phosphate and Sphingosine‐1‐Phosphate Receptor 3 Signaling Worsens Liver Ischemia/Reperfusion Injury by Regulating M1/M2 Polarization

Hyperglycemia aggravates hepatic ischemia/reperfusion injury (IRI), but the underlying mechanism for the aggravation remains elusive. Sphingosine‐1‐phosphate (S1P) and sphingosine‐1‐phosphate receptors (S1PRs) have been implicated in metabolic and inflammatory diseases. Here, we discuss whether and...

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書誌詳細
出版年:Liver Transpl
主要な著者: Hu, Yuanchang, Yang, Chao, Shen, Gefengqiang, Yang, Shikun, Cheng, Xuyu, Cheng, Feng, Rao, Jianhua, Wang, Xuehao
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617772/
https://ncbi.nlm.nih.gov/pubmed/30972941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.25470
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