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Sphingosine Kinase 1 and Sphingosine-1-Phosphate Signaling in Colorectal Cancer

Sphingosine kinase 1 (Sphk1) is a highly conserved lipid kinase that phosphorylates sphingosine to form sphingosine-1-phosphate (S1P). Growing studies have demonstrated that Sphk1 is overexpressed in various types of solid cancers and can be induced by growth factors, cytokines, and carcinogens, lea...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bao, Yonghua, Guo, Yongchen, Zhang, Chenglan, Fan, Fenghua, Yang, Wancai
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666791/
https://ncbi.nlm.nih.gov/pubmed/28991193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18102109
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