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Roles of sphingosine-1-phosphate signaling in cancer

The potent pleiotropic lipid mediator sphingosine-1-phosphate (S1P) participates in numerous cellular processes, including angiogenesis and cell survival, proliferation, and migration. It is formed by one of two sphingosine kinases (SphKs), SphK1 and SphK2. These enzymes largely exert their various...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Wang, Peng, Yuan, Yonghui, Lin, Wenda, Zhong, Hongshan, Xu, Ke, Qi, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857321/
https://ncbi.nlm.nih.gov/pubmed/31807117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-1014-8
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