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Targeting the Sphingosine Kinase/Sphingosine-1-Phosphate Signaling Axis in Drug Discovery for Cancer Therapy
SIMPLE SUMMARY: Cancer is the prime cause of death globally. The altered stimulation of signaling pathways controlled by human kinases has often been observed in various human malignancies. The over-expression of SphK1 (a lipid kinase) and its metabolite S1P have been observed in various types of ca...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cancers (Basel) |
|---|---|
| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
MDPI
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8071327/ https://ncbi.nlm.nih.gov/pubmed/33920887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081898 |
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