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Identification of Sphingosine Kinase-1 Inhibitors from Bioactive Natural Products Targeting Cancer Therapy
[Image: see text] Sphingosine kinase 1 (SphK1) is an oncogenic lipid kinase that catalyzes the formation of sphingosine-1-phosphate via phosphorylation of sphingosine and known to play a crucial role in angiogenesis, lymphocyte trafficking, signal transduction pathways, and response to apoptotic sti...
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| Pubblicato in: | ACS Omega |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2020
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7315586/ https://ncbi.nlm.nih.gov/pubmed/32596609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c01511 |
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