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Identification of Sphingosine Kinase-1 Inhibitors from Bioactive Natural Products Targeting Cancer Therapy

[Image: see text] Sphingosine kinase 1 (SphK1) is an oncogenic lipid kinase that catalyzes the formation of sphingosine-1-phosphate via phosphorylation of sphingosine and known to play a crucial role in angiogenesis, lymphocyte trafficking, signal transduction pathways, and response to apoptotic sti...

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Bibliografske podrobnosti
izdano v:ACS Omega
Main Authors: Jairajpuri, Deeba Shamim, Mohammad, Taj, Adhikari, Kirtika, Gupta, Preeti, Hasan, Gulam Mustafa, Alajmi, Mohamed F., Rehman, Md. Tabish, Hussain, Afzal, Hassan, Md. Imtaiyaz
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315586/
https://ncbi.nlm.nih.gov/pubmed/32596609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c01511
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