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Hyperglycemia‐Triggered Sphingosine‐1‐Phosphate and Sphingosine‐1‐Phosphate Receptor 3 Signaling Worsens Liver Ischemia/Reperfusion Injury by Regulating M1/M2 Polarization

Hyperglycemia aggravates hepatic ischemia/reperfusion injury (IRI), but the underlying mechanism for the aggravation remains elusive. Sphingosine‐1‐phosphate (S1P) and sphingosine‐1‐phosphate receptors (S1PRs) have been implicated in metabolic and inflammatory diseases. Here, we discuss whether and...

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Vydáno v:Liver Transpl
Hlavní autoři: Hu, Yuanchang, Yang, Chao, Shen, Gefengqiang, Yang, Shikun, Cheng, Xuyu, Cheng, Feng, Rao, Jianhua, Wang, Xuehao
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617772/
https://ncbi.nlm.nih.gov/pubmed/30972941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.25470
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