Hyperglycemia‐Triggered Sphingosine‐1‐Phosphate and Sphingosine‐1‐Phosphate Receptor 3 Signaling Worsens Liver Ischemia/Reperfusion Injury by Regulating M1/M2 Polarization

Hyperglycemia aggravates hepatic ischemia/reperfusion injury (IRI), but the underlying mechanism for the aggravation remains elusive. Sphingosine‐1‐phosphate (S1P) and sphingosine‐1‐phosphate receptors (S1PRs) have been implicated in metabolic and inflammatory diseases. Here, we discuss whether and...

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Enregistré dans:
Détails bibliographiques
Publié dans:Liver Transpl
Auteurs principaux: Hu, Yuanchang, Yang, Chao, Shen, Gefengqiang, Yang, Shikun, Cheng, Xuyu, Cheng, Feng, Rao, Jianhua, Wang, Xuehao
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617772/
https://ncbi.nlm.nih.gov/pubmed/30972941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.25470
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