Hyperglycemia‐Triggered Sphingosine‐1‐Phosphate and Sphingosine‐1‐Phosphate Receptor 3 Signaling Worsens Liver Ischemia/Reperfusion Injury by Regulating M1/M2 Polarization

Hyperglycemia aggravates hepatic ischemia/reperfusion injury (IRI), but the underlying mechanism for the aggravation remains elusive. Sphingosine‐1‐phosphate (S1P) and sphingosine‐1‐phosphate receptors (S1PRs) have been implicated in metabolic and inflammatory diseases. Here, we discuss whether and...

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Dades bibliogràfiques
Publicat a:Liver Transpl
Autors principals: Hu, Yuanchang, Yang, Chao, Shen, Gefengqiang, Yang, Shikun, Cheng, Xuyu, Cheng, Feng, Rao, Jianhua, Wang, Xuehao
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617772/
https://ncbi.nlm.nih.gov/pubmed/30972941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.25470
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