Mapping the drivers of within-host pathogen evolution using massive data sets

Differences among hosts, resulting from genetic variation in the immune system or heterogeneity in drug treatment, can impact within-host pathogen evolution. Genetic association studies can potentially identify such interactions. However, extensive and correlated genetic population structure in host...

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Foilsithe in:Nat Commun
Main Authors: Palmer, Duncan S., Turner, Isaac, Fidler, Sarah, Frater, John, Goedhals, Dominique, Goulder, Philip, Huang, Kuan-Hsiang Gary, Oxenius, Annette, Phillips, Rodney, Shapiro, Roger, Vuuren, Cloete van, McLean, Angela R., McVean, Gil
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616926/
https://ncbi.nlm.nih.gov/pubmed/31289267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10724-w
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