Maintenance of Functional CD57+ Cytolytic CD4+ T Cells in HIV+ Elite Controllers

Cytolytic CD4+ T cells play a prominent role in chronic viral infection. CD4+ CTLs clones specific for HIV-1 Nef and Gag are capable of killing HIV-1 infected CD4+ T cells and macrophages. Additionally, HIV-specific cytolytic CD4+ T cell responses in acute HIV infection are predictive of disease pro...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Phetsouphanh, Chansavath, Aldridge, Daniel, Marchi, Emanuele, Munier, C. Mee Ling, Meyerowitz, Jodi, Murray, Lyle, Van Vuuren, Cloete, Goedhals, Dominique, Fidler, Sarah, Kelleher, Anthony, Klenerman, Paul, Frater, John
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694780/
https://ncbi.nlm.nih.gov/pubmed/31440240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01844
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