Single-cell transcriptome analysis of CD8 (+) T-cell memory inflation

Background: Persistent viruses such as murine cytomegalovirus (MCMV) and adenovirus-based vaccines induce strong, sustained CD8 (+) T-cell responses, described as memory “inflation”. These retain functionality, home to peripheral organs and are associated with a distinct transcriptional program. Met...

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Pubblicato in:Wellcome Open Res
Autori principali: Highton, Andrew J., Zinser, Madeleine E., Lee, Lian Ni, Hutchings, Claire L., De Lara, Catherine, Phetsouphanh, Chansavath, Willberg, Chris B., Gordon, Claire L., Klenerman, Paul, Marchi, Emanuele
Natura: Artigo
Lingua:Inglês
Pubblicazione: F1000 Research Limited 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688724/
https://ncbi.nlm.nih.gov/pubmed/31448339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.15115.1
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