Adenoviral vaccine induction of CD8(+) T cell memory inflation: Impact of co-infection and infection order

The efficacies of many new T cell vaccines rely on generating large populations of long-lived pathogen-specific effector memory CD8 T cells. However, it is now increasingly recognized that prior infection history impacts on the host immune response. Additionally, the order in which these infections...

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Udgivet i:PLoS Pathog
Main Authors: Lee, Lian N., Bolinger, Beatrice, Banki, Zoltan, de Lara, Catherine, Highton, Andrew J., Colston, Julia M., Hutchings, Claire, Klenerman, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760110/
https://ncbi.nlm.nih.gov/pubmed/29281733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006782
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