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Genetic interactions of G-quadruplexes in humans

G-quadruplexes (G4) are alternative nucleic acid structures involved in transcription, translation and replication. Aberrant G4 formation and stabilisation is linked to genome instability and cancer. G4 ligand treatment disrupts key biological processes leading to cell death. To discover genes and p...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zyner, Katherine G, Mulhearn, Darcie S, Adhikari, Santosh, Martínez Cuesta, Sergio, Di Antonio, Marco, Erard, Nicolas, Hannon, Gregory J, Tannahill, David, Balasubramanian, Shankar
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615864/
https://ncbi.nlm.nih.gov/pubmed/31287417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46793
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