Examining the Impact of Imputation Errors on Fine-Mapping Using DNA Methylation QTL as a Model Trait

Genetic variants disrupting DNA methylation at CpG dinucleotides (CpG-SNP) provide a set of known causal variants to serve as models to test fine-mapping methodology. We use 1716 CpG-SNPs to test three fine-mapping approaches (Bayesian imputation-based association mapping, Bayesian sparse linear mix...

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Detaylı Bibliyografya
Yayımlandı:Genetics
Asıl Yazarlar: Chundru, V. Kartik, Marioni, Riccardo E., Prendergast, James G. D., Vallerga, Costanza L., Lin, Tian, Beveridge, Allan J., Gratten, Jacob, Hume, David A., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2019
Konular:
Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614908/
https://ncbi.nlm.nih.gov/pubmed/31040117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301861
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