Genotype effects contribute to variation in longitudinal methylome patterns in older people

BACKGROUND: DNA methylation levels change along with age, but few studies have examined the variation in the rate of such changes between individuals. METHODS: We performed a longitudinal analysis to quantify the variation in the rate of change of DNA methylation between individuals using whole bloo...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Zhang, Qian, Marioni, Riccardo E, Robinson, Matthew R, Higham, Jon, Sproul, Duncan, Wray, Naomi R, Deary, Ian J, McRae, Allan F, Visscher, Peter M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198530/
https://ncbi.nlm.nih.gov/pubmed/30348214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0585-7
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