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Structure-based virtual screening leading to discovery of highly selective butyrylcholinesterase inhibitors with solanaceous alkaloid scaffolds

According to recent research advance, it is interesting to identify new, potent and selective inhibitors of human butyrylcholinesterase (BChE) for therapeutic treatment of both the Alzheimer’s disease (AD) and heroin abuse. In this study, we carried out a structure-based virtual screening followed b...

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Detaylı Bibliyografya
Yayımlandı:Chem Biol Interact
Asıl Yazarlar: Zhou, Shuo, Yuan, Yaxia, Zheng, Fang, Zhan, Chang-Guo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613991/
https://ncbi.nlm.nih.gov/pubmed/31152736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2019.05.051
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