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Structure-based virtual screening leading to discovery of highly selective butyrylcholinesterase inhibitors with solanaceous alkaloid scaffolds
According to recent research advance, it is interesting to identify new, potent and selective inhibitors of human butyrylcholinesterase (BChE) for therapeutic treatment of both the Alzheimer’s disease (AD) and heroin abuse. In this study, we carried out a structure-based virtual screening followed b...
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| Опубликовано в: : | Chem Biol Interact |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6613991/ https://ncbi.nlm.nih.gov/pubmed/31152736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2019.05.051 |
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