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Lysosomal inhibition attenuates peroxisomal gene transcription via suppression of PPARA and PPARGC1A levels

Lysosomes influence dynamic cellular processes such as nutrient sensing and transcriptional regulation. To explore novel transcriptional pathways regulated by lysosomes, we performed microarray analysis followed by qPCR validation in a mouse hepatocyte cell line, AML12, treated with bafilomycin A(1)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Autophagy
Egile Nagusiak: Siong Tan, Hayden Weng, Anjum, B., Shen, Han-Ming, Ghosh, Sujoy, Yen, Paul M., Sinha, Rohit A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613898/
https://ncbi.nlm.nih.gov/pubmed/31032705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1609847
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