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Lysosomal inhibition attenuates peroxisomal gene transcription via suppression of PPARA and PPARGC1A levels
Lysosomes influence dynamic cellular processes such as nutrient sensing and transcriptional regulation. To explore novel transcriptional pathways regulated by lysosomes, we performed microarray analysis followed by qPCR validation in a mouse hepatocyte cell line, AML12, treated with bafilomycin A(1)...
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| Publicado no: | Autophagy |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6613898/ https://ncbi.nlm.nih.gov/pubmed/31032705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1609847 |
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