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Loss of ULK1 Attenuates Cholesterogenic Gene Expression in Mammalian Hepatic Cells
The hepatic mevalonate (MVA) pathway, responsible for cholesterol biosynthesis, is a therapeutically important metabolic pathway in clinical medicine. Using an unbiased transcriptomics approach, we uncover a novel role of Unc-51 like autophagy activating kinase 1 (ULK1) in regulating the expression...
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| Publié dans: | Front Cell Dev Biol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7554540/ https://ncbi.nlm.nih.gov/pubmed/33083385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.523550 |
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