Activation of Peroxisome Proliferator-activated Receptor α Induces Lysosomal Biogenesis in Brain Cells: IMPLICATIONS FOR LYSOSOMAL STORAGE DISORDERS

Lysosomes are ubiquitous membrane-enclosed organelles filled with an acidic interior and are central to the autophagic, endocytic, or phagocytic pathway. In contrast to its classical function as the waste management machinery, lysosomes are now considered to be an integral part of various cellular s...

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Vydáno v:J Biol Chem
Hlavní autoři: Ghosh, Arunava, Jana, Malabendu, Modi, Khushbu, Gonzalez, Frank J., Sims, Katherine B., Berry-Kravis, Elizabeth, Pahan, Kalipada
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400343/
https://ncbi.nlm.nih.gov/pubmed/25750174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610659
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