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Activation of Peroxisome Proliferator-activated Receptor α Induces Lysosomal Biogenesis in Brain Cells: IMPLICATIONS FOR LYSOSOMAL STORAGE DISORDERS

Lysosomes are ubiquitous membrane-enclosed organelles filled with an acidic interior and are central to the autophagic, endocytic, or phagocytic pathway. In contrast to its classical function as the waste management machinery, lysosomes are now considered to be an integral part of various cellular s...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ghosh, Arunava, Jana, Malabendu, Modi, Khushbu, Gonzalez, Frank J., Sims, Katherine B., Berry-Kravis, Elizabeth, Pahan, Kalipada
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400343/
https://ncbi.nlm.nih.gov/pubmed/25750174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610659
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