Chargement en cours...
Hexokinase II promotes the Warburg effect by phosphorylating alpha subunit of pyruvate dehydrogenase
OBJECTIVE: Tumor cells rely heavily on glycolysis regardless of oxygen tension, a phenomenon called the Warburg effect. Hexokinase II (HKII) catalyzes the first irreversible step of glycolysis and is often overexpressed in tumor cells. Mitochondrial HKII couples glycolysis and oxidative phosphorylat...
Enregistré dans:
| Publié dans: | Chin J Cancer Res |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
AME Publishing Company
2019
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6613503/ https://ncbi.nlm.nih.gov/pubmed/31354221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21147/j.issn.1000-9604.2019.03.14 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|