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How the avidity of polymerase binding to the –35/–10 promoter sites affects gene expression

Although the key promoter elements necessary to drive transcription in Escherichia coli have long been understood, we still cannot predict the behavior of arbitrary novel promoters, hampering our ability to characterize the myriad sequenced regulatory architectures as well as to design new synthetic...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Einav, Tal, Phillips, Rob
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613100/
https://ncbi.nlm.nih.gov/pubmed/31196959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905615116
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