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How the avidity of polymerase binding to the –35/–10 promoter sites affects gene expression

Although the key promoter elements necessary to drive transcription in Escherichia coli have long been understood, we still cannot predict the behavior of arbitrary novel promoters, hampering our ability to characterize the myriad sequenced regulatory architectures as well as to design new synthetic...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Einav, Tal, Phillips, Rob
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613100/
https://ncbi.nlm.nih.gov/pubmed/31196959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905615116
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