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How the avidity of polymerase binding to the –35/–10 promoter sites affects gene expression

Although the key promoter elements necessary to drive transcription in Escherichia coli have long been understood, we still cannot predict the behavior of arbitrary novel promoters, hampering our ability to characterize the myriad sequenced regulatory architectures as well as to design new synthetic...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Einav, Tal, Phillips, Rob
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613100/
https://ncbi.nlm.nih.gov/pubmed/31196959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905615116
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