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Theoretical analysis of inducer and operator binding for cyclic-AMP receptor protein mutants

Allosteric transcription factors undergo binding events at inducer binding sites as well as at distinct DNA binding domains, and it is difficult to disentangle the structural and functional consequences of these two classes of interactions. We compare the ability of two statistical mechanical models...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Einav, Tal, Duque, Julia, Phillips, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157895/
https://ncbi.nlm.nih.gov/pubmed/30256816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204275
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