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Clinical mutational profiling and categorization of BRAF mutations in melanomas using next generation sequencing
BACKGROUND: Analysis of melanomas for actionable mutations has become the standard of care. Recently, a classification scheme has been proposed that categorizes BRAF mutations based on their mechanisms for activation of the MAPK pathway. METHODS: In this analysis BRAF, KIT, NRAS, and PIK3CA mutation...
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| Publicado no: | BMC Cancer |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6612071/ https://ncbi.nlm.nih.gov/pubmed/31277584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5864-1 |
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