Clinical mutational profiling of 1006 lung cancers by next generation sequencing

Analysis of lung adenocarcinomas for actionable mutations has become standard of care. Here, we report our experience using next generation sequencing (NGS) to examine AKT1, BRAF, EGFR, ERBB2, KRAS, NRAS, and PIK3CA genes in 1006 non-small cell lung cancers in a clinical diagnostic setting. NGS demo...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Illei, Peter B., Belchis, Deborah, Tseng, Li-Hui, Nguyen, Doreen, De Marchi, Federico, Haley, Lisa, Riel, Stacy, Beierl, Katie, Zheng, Gang, Brahmer, Julie R., Askin, Frederic B., Gocke, Christopher D., Eshleman, James R., Forde, Patrick M., Lin, Ming-Tseh
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722514/
https://ncbi.nlm.nih.gov/pubmed/29228562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18042
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