Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers

Activating mutations in downstream genes of the epidermal growth factor receptor (EGFR) pathway may cause anti-EGFR resistance in patients with colorectal cancers. We present performance characteristics of a next-generation sequencing assay designed to detect such mutations. In this retrospective qu...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Haley, Lisa, Tseng, Li-Hui, Zheng, Gang, Dudley, Jonathan, Anderson, Derek A, Azad, Nilofer S, Gocke, Christopher D, Eshleman, James R, Lin, Ming-Tseh
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618462/
https://ncbi.nlm.nih.gov/pubmed/26226847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2015.86
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