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Clinical validation of coexisting driver mutations in colorectal cancers

Mutational profiling is recommended for selecting targeted therapy and predicting prognosis of metastatic colorectal cancer (CRC). Detection of coexisting mutations within the same pathway, which are usually mutually exclusive, raises the concern for potential laboratory errors. In this retrospectiv...

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Detalhes bibliográficos
Publicado no:Hum Pathol
Main Authors: Zheng, Gang, Tseng, Li-Hui, Haley, Lisa, Ibrahim, Junaid, Bynem, Jennifer, Xian, Rena, Gocke, Christopher D., Eshleman, James R., Lin, Ming-Tseh
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467705/
https://ncbi.nlm.nih.gov/pubmed/30481508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2018.11.014
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