Control of LDL Uptake in Human Cells by Targeting the LDLR Regulatory Long Non-coding RNA BM450697

Hypercholesterolemia is a condition that is characterized by very high levels of cholesterol in the blood and is a major correlating factor with heart disease. Indeed, high levels of the low-density lipoprotein (LDL) have been causally linked to the development of atherosclerotic cardiovascular dise...

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Bibliographic Details
Published in:Mol Ther Nucleic Acids
Main Authors: Ray, Roslyn M., Hansen, Anders Højgaard, Slott, Sofie, Taskova, Maria, Astakhova, Kira, Morris, Kevin V.
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611981/
https://ncbi.nlm.nih.gov/pubmed/31279228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.05.024
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