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“Clicking” gene therapeutics: A successful union of chemistry and biomedicine for new solutions

The use of nucleic acid, DNA and RNA, based strategies to disrupt gene expression as a therapeutic is quickly emerging. Indeed, synthetic oligonucleotides represent a major component of emerging gene therapeutics. However, the efficiency and specificity of intracellular uptake for non-modified oligo...

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Bibliografische gegevens
Gepubliceerd in:Mol Pharm
Hoofdauteurs: Astakhova, Kira, Ray, Roslyn, Taskova, Maria, Uhd, Jesper, Carstens, Annika, Morris, Kevin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078818/
https://ncbi.nlm.nih.gov/pubmed/29300491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00765
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