Lunasin functionally enhances LDL uptake via inhibiting PCSK9 and enhancing LDLR expression in vitro and in vivo

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease which regulates serum low-density lipoprotein cholesterol (LDL-C) levels by promoting the degradation of the hepatic low-density lipoprotein receptor (LDLR), and has become an attractive therapeutic target for cholesterol low...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Gu, Lili, Wang, Yue, Xu, Yaqiong, Tian, Qinghua, Lei, Gaoxin, Zhao, Cheng, Gao, Zhan, Pan, Qin, Zhao, Wenfeng, Nong, Liu, Tan, Shuhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655242/
https://ncbi.nlm.nih.gov/pubmed/29113347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20590
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