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Unusual, stable replicating viruses generated from mumps virus cDNA clones

In reverse genetic experiments we have isolated recombinant mumps viruses (rMuV) that carry large numbers of mutations clustered in small parts of their genome, which are not caused by biased hyper-mutation. In two separate experiments we obtained such recombinant viruses: one virus had 11 mutations...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Bamford, Connor, Wignall-Fleming, Elizabeth, Sreenu, Vattipally B., Randall, Richard, Duprex, Paul, Rima, Bertus
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611571/
https://ncbi.nlm.nih.gov/pubmed/31276568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219168
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