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Unusual, stable replicating viruses generated from mumps virus cDNA clones

In reverse genetic experiments we have isolated recombinant mumps viruses (rMuV) that carry large numbers of mutations clustered in small parts of their genome, which are not caused by biased hyper-mutation. In two separate experiments we obtained such recombinant viruses: one virus had 11 mutations...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Bamford, Connor, Wignall-Fleming, Elizabeth, Sreenu, Vattipally B., Randall, Richard, Duprex, Paul, Rima, Bertus
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611571/
https://ncbi.nlm.nih.gov/pubmed/31276568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219168
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