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A Point Mutation, E95D, in the Mumps Virus V Protein Disengages STAT3 Targeting from STAT1 Targeting

Mumps virus, like other paramyxoviruses in the Rubulavirus genus, encodes a V protein that can assemble a ubiquitin ligase complex from cellular components, leading to the destruction of cellular signal transducer and activator of transcription (STAT) proteins. While many V proteins target the inter...

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Detalhes bibliográficos
Main Authors: Puri, Mamta, Lemon, Ken, Duprex, W. Paul, Rima, Bertus K., Horvath, Curt M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698558/
https://ncbi.nlm.nih.gov/pubmed/19386700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00596-09
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