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GAS41 recognizes di-acetylated histone H3 through a bivalent binding mode

GAS41 is a chromatin-associated protein that belongs to the YEATS family and is involved in the recognition of acetyl-lysine in histone proteins. A unique feature of GAS41 is the presence of a C-terminal coiled-coil domain, which is responsible for protein dimerization. Here, we characterized specif...

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Pubblicato in:ACS Chem Biol
Autori principali: Je Cho, Hyo, Li, Hao, Linhares, Brian M., Kim, EunGi, Ndoj, Juliano, Miao, Hongzhi, Grembecka, Jolanta, Cierpicki, Tomasz
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611172/
https://ncbi.nlm.nih.gov/pubmed/30071723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00674
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