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Structure, Function, and Dynamics of the Gα Binding Domain of Ric-8A
Ric-8A is a 530-amino acid cytoplasmic molecular chaperone and guanine nucleotide exchange factor (GEF) for i, q, and 12/13 classes of heterortrimeric G protein alpha subunits (Gα). We report the 2.2-Å crystal structure of the Ric-8A Gα-binding domain with GEF activity, residues 1–452, and is phosph...
Shranjeno v:
| izdano v: | Structure |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6610710/ https://ncbi.nlm.nih.gov/pubmed/31155309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.04.013 |
| Oznake: |
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