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Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits

We have shown that resistance to inhibitors of cholinesterase 8 (Ric-8) proteins regulate an early step of heterotrimeric G protein α (Gα) subunit biosynthesis. Here, mammalian and plant cell-free translation systems were used to study Ric-8A action during Gα subunit translation and protein folding....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chan, PuiYee, Thomas, Celestine J., Sprang, Stephen R., Tall, Gregory G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593926/
https://ncbi.nlm.nih.gov/pubmed/23431197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220943110
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