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Effects of the α2/α3-subtype-selective GABA(A) receptor positive allosteric modulator KRM-II-81 on pain-depressed behavior in rats: Comparison with ketorolac and diazepam

This study examined effects of the α2/α3-subtype-selective GABA(A) receptor positive allosteric modulator KRM-II-81 in an assay of pain-related behavioral depression. Adult, male Sprague-Dawley rats responded for electrical brain stimulation in a frequency-rate intracranial self-stimulation (ICSS) p...

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Detalhes bibliográficos
Publicado no:Behav Pharmacol
Main Authors: Moerke, Megan J., Li, Guanguan, Golani, Lalit K., Cook, James, Negus, S. Stevens
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610697/
https://ncbi.nlm.nih.gov/pubmed/30640180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0000000000000464
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